A meta-analysis of soluble suppression of tumorigenicity 2 (sST2) and clinical outcomes in pulmonary hypertension
نویسندگان
چکیده
King Sum Luk, Christina Ip, Meng–Qi GONG, Sunny Hei WONG, William KK Wu, Mei DONG, Guang–Ping LI, Ka Pang Chan, Yi–Mei DU, Tong LIU, Martin CS Wong, David Shu Cheong Hui, Gary Tse, International Health Informatics Study (IHIS) Network 1 Department of Medicine and Therapeutics, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, China 2 Li Ka Shing Institute of Health Sciences, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, China 3 Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, China 4 Department of Anaesthesia and Intensive Care, State Key Laboratory of Digestive Disease, LKS Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China 5 The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Qilu Hospital, Shandong University, Jinan, China 6 Research Center of Ion Channelopathy, Institute of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China 7 JC School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China 8 State Key Laboratory of Digestive Disease, LKS Institute of Health Sciences, Chinese University of Hong Kong, Hong Kong, China
منابع مشابه
Soluble Suppression of Tumorigenicity 2 and Echocardiography in Sepsis
Soluble suppression of tumorigenicity 2 (sST2) has emerged as a biomarker of cardiac stretch or remodeling, and has demonstrated a role in acutely decompensated heart failure. However, its role in sepsis-induced cardiac dysfunction is still unknown. We explored whether sST2 serum concentration reflects either systolic or diastolic dysfunction as measured by Doppler echocardiography. In a total ...
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OBJECTIVE Soluble suppression of tumorigenicity-2 (sST2), a member of the interleukin 1 receptor family, is increased in mechanical stress conditions and is produced by cardiomyocytes and cardiac fibroblasts. Elevated sST2 level is associated with the prognosis of acute coronary syndrome, pulmonary arterial hypertension, and acute and chronic heart failure (HF). In this study, we aimed to inves...
متن کاملSoluble suppression of tumorigenicity-2 for risk stratification in outpatients with heart failure
I have read the article by Gül et al. (1) entitled “Prognostic role of soluble suppression of tumorigenicity-2 on cardiovascular mortality in outpatients with heart failure,” which was published in Anatol J Cardiol 2017; 18: 200-5, with great interest. In their study, the authors reported that baseline levels of soluble suppression of tumorigenicity-2 (sST2) are an independent predictor of mort...
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BACKGROUND Soluble suppression of tumorigenicity 2 (sST2) has emerged as a novel biomarker for heart failure, and serum sST2 concentrations could be increased in inflammatory diseases. We explored whether sST2 is related to cardiac dysfunction/failure and has a prognostic role in patients with suspected sepsis. METHODS In a total of 397 patients with suspected sepsis, sST2 concentrations were...
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Background Heart failure (HF) in infants and children with congenital heart disease (CHD) is a crucial complication with different outcomes. Many biomarkers are used as prognostic indicators. Soluble ST2 (sST2) is one of these markers studied in adults with HF. We aimed to study the prognostic value of sST2 in CHD children with HF. Materials and Methods In current case-control study, thirty-six...
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